GanedenBC30 is an amazing probiotic ingredient that is used in foods and drinks.
The World Health Organization (WHO) defines probiotics as “live microorganisms, which, when taken in adequate amounts, offer a
How do I choose a probiotic?
Not all probiotics strains are the same. Different strains offer different benefits and some probiotic strains survive manufacturing processes, shelf life and digestive transit better than others. When choosing a probiotic consider the following:
- Is it safe and has the FDA reviewed the safety data?
- Does it survive the extremes of manufacturing?
- Does it survive the shelf life of the product?
- Will it survive digestive transit?
- Is there published research to support it?
GanedenBC30 is a natural probiotic (“beneficial bacteria”) ingredient added to many foods, beverages and supplements to help support digestive and immune health*
- The trademarked name for the patented strain of probiotic bacteria, Bacillus coagulansGBI-30, 6086.
- An ingredient in foods, beverages and supplements.
- Safe – It’s NOT a drug – as per our FDA GRAS affirmation.
- Clinically studied and supported by over 20 peer reviewed, published papers.
- Calorie and gluten-free.
- Organic Compliant.
- Kosher and halal.
- A sustainable, naturally occurring, non-GMO ingredient – no “engineering” here.
- Used as an ingredient, ONLY to provide added health benefits to consumers. GanedenBC30will not change the composition or taste of any product.
Ganeden has conducted extensive safety studies on GanedenBC30, which have been published (Endres 2009, Endres2011) and culminated with Ganeden receiving FDA GRAS. These tests prove that even when GanedenBC30 is consumed at much higher levels than what is found in food and beverage products, that there are no safety concerns. FDA GRAS is strain specific, and GanedenBC30 is the only Bacillus that has been granted FDA GRAS status.
Safety Assessment Of A Proprietary Preparation Of A Novel Probiotic, Bacillus Coagulans, As A Food Ingredient
Food and Chemical Toxicology, 2009; 47: 1231–1238
J.R. Endresa, A. Clewella, K.A. Jadea, T. Farberb, J. Hauswirthc A.G. Schaussa
One-Year Chronic Oral Toxicity With Combined Reproduction Toxicity Study Of A Novel Probiotic, Bacillus Coagulans, As A Food Ingredient
Food and Chemical Toxicology Article in Press
J.R. Endresa, I. Qureshia, T. Farberb, J. Hauswirthc, G. Hirkad, I. Pasicsd, A.G. Schaussa
In multiple studies, GanedenBC30 supports digestive health when consumed daily:
A Prospective, Randomized, Double–blind, Placebo–controlled Parallel–group Dual Site Trial To Evaluate The Effects Of A Bacillus Coagulans–based Product On Functional Intestinal Gas Symptoms
BMC Gastroenterology, 2009, 9:85
Douglas S Kalman, Howard I Schwartz, Patricia Alvarez, Samantha Feldman, John C Pezzullo and Diane R Krieger
Survival And Metabolic Activity Of The GanedenBC30 Strain Of Bacillus Coagulans In A Dynamic In Vitro Model Of The Stomach And Small Intestine
Beneficial Microbes, 2010; 1(1): 31–36
A.J.H Maathuis, D. Keller, S. Farmer
Impact of GanedenBC30 (Bacillus coagulans GBI-30, 6086) on population dynamics of the human gut microbiota in a continuous culture fermentation system
International Journal of Probiotics and Prebiotics, 2011, 6 (1): 65-72
Harue Honda, Lesley Hoyles, Glenn R. Gibson, Sean Farmer, David Keller and Anne L. McCartney
Use Of A Continuous Culture Fermentation System To Investigate The Effect Of GanedenBC30 Bacillus CoagulansGBI-30, 6086) Supplementation On Pathogen Survival In The Human Gut Microbiota
Anarobe 2011, 17 (1): 36-42
H. Honda, G.R. Gibsona, S. Farmerb, D. Kellerb, A.L. McCartneya
Bacillus Coagulans GBI-30 (BC30) improves indices of Clostridium difficile-Induced colitis in mice
Gut Pathogens, 2011, 3:16
Leo R Fitzpatrick, Jeffrey S Small, Wallace H Greene, Kelly D Karpa and David Keller
Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice
Gut Pathogens, 2012, 4:13
Leo R Fitzpatrick, Jeffrey S Small, Wallace H Greene, Kelly D Karpa, Sean Farmer and David Keller
Bacillus Coagulans Significantly Improved Abdominal Pain And Bloating In Patients With IBS
Postgraduate Medicine, 2009; 121(2): 119–124
Effects Of A Proprietary Bacillus Coagulans Preparation On Symptoms Of Diarrhea–Predominant Irritable Bowel Syndrome
Methods Find Exp Clin Pharmacol 2009; 31(10): 655–659
A large majority of the body’s immune system is located within the intestines. When GanedenBC30 is consumed daily, it creates a healthier intestinal environment, supporting immune function.
Bacillus coagulans GBI-30, 6086 Modulates Faecalibacterium prausnitzii in Older Men and Women
The Journal of Nutrition May 2015
Edna P Nyangale, Sean Farmer, Howard A Cash, David Keller, David Chernoff, and Glenn R Gibson
Immunomodulation of Antiretroviral Drug-Suppressed Chronic HIV-1 Infection in an Oral Probiotic Double-Blind Placebo-Controlled Trial
AIDS Research and Human Retroviruses October 2014, 30(10): 988-995. doi:10.1089/aid.2014.0181.
Yang Otto O., Kelesidis Theodoros, Cordova Robert, and Khanlou Homayoon
GanedenBC30 Cell Wall And Metabolites: Anti–inflammatory And Immune Modulating Effects In vitro
BMC Immunology 2010, 11:15
Gitte S Jensen, Kathleen F Benson, Steve G Carter, John R Endres
Probiotic metabolites from Bacillus coagulans GanedenBC30 support maturation of antigen-presenting cells in vitro
World Journal of Gastroenterology, 2012, 18(16): 1875–1883
Kathleen F Benson, Kimberlee A Redman, Steve G Carter, David Keller, Sean Farmer, John R Endres and Gitte S Jensen
A review of probiotics studies in HIV research suggests improved immunological presentation and preservation of viral host restrictive factors of TH17 in HIV patients
Retrovirology, 2012, 9(Suppl 1):P22
M Selbovitz, Keller, Miller, Moore, Farmer and Bray
A Patented Strain Of Bacillus Coagulans Increased Immune Response To Viral Challenge
Postgraduate Medicine, 2009; 121(2): 114–118
A Controlled Clinical Trial To Evaluate The Effect of GanedenBC30 On Immunological Markers
Methods and Findings in Experimental and Clinical Pharmacology 2010, 32(2): 129-132
M. Kimmel, D. Keller, S. Farmer, D.E. Warrino
Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery
PeerJ, July 2016
Ralf Jäger, Kevin A. Shields, Ryan P. Lowery, Eduardo O. De Souza, Jeremy M. Partl, Chase Hollmer, Martin Purpura and Jacob M. Wilson
Effect of prebiotics on the fecal microbiota of elderly volunteers after dietary supplementation of Bacillus coagulans GBI-30, 6086
Anaerobe Volume 30, December 2014, Pages 75–81
Edna P. Nyangale, Sean Farmer, David Keller, David Chernoff, Glenn R. Gibson
Bacillus coagulans : A Viable Adjunct Therapy For Relieving Symptoms Of Rheumatoid Arthritis According To A Randomized, Controlled Trial
BMC Complementary and Alternative Medicine 2010, 10:1
David R Mandel, Katy Eichas, Judith Holmes
Bacillus Coagulans As A Probiotic
Food Science & Technology Bulletin: Functional Foods 2010, 7 (7): 103-109
D. Keller, S. Farmer, A.L. McCartney, G. Gibson